In all NPC evaluated tissue specimens, there was a significant correlation between the expression of β-catenin and EBV DNA, EBV-VCA-IgA, EBV-EA-IgA, T stage, N stage, and clinicopathological stages of NPC (all P < 0.05), with no significant correlations in gender, age, smoking history, family history, and histological classification (all P > 0.05). The gene discussed is CD79A; the disease is nasopharyngeal carcinoma.