In AIPpos tumors we identified a significant number of altered EMT-associated genes, including epithelial markers (CDH1, CTNNB1, ERSP1, and EPCAM), a transcriptional (ZEB1) and a post-transcriptional regulator (ESRP1), while there were no statistically significant differences between sporadic adenomas and normal pituitaries. The gene discussed is EPCAM; the disease is adenoma.