CBLN1 and Anxiety: For example, these authors reported that cbln1 null mice and mice that were deficient of Cbln1 primarily in the cerebellum (cb-cbln1 null mice), each remained in the central area of an open-field for a greater period of time during a brief (5-min) test compared to controls, suggesting less anxiety-like behavior, and each also exhibited acquisition deficits in contextual fear and auditory cue conditioning.