MKI67 and neoplasm: On the other hand, patient overall survival time and patient outcome were negatively correlated with Ki-67 levels (rs = −0.286, p < 0.001), patient age (rs = −0.258, p = 0.002), tumor grade (τ = −0.188, p = 0.002; log-rank test: p < 0.001), size (log-rank test: p < 0.001), stage (τ = 0.259, p < 0.001; log-rank test: p < 0.001) and (as mentioned already above) presence of distant MTS.