Within ME black, corresponding to WM microglia in both control and MS tissue, top enriched hallmark pathways were “TNFα signaling via NF-κB,” “oxidative phosphorylation,” and “cholesterol homeostasis.” Enriched GO terms were “microtubule based movement” and “chemotaxis” (Fig. 3b). Here, NFKB1 is linked to myeloid sarcoma.