Tables 2 and 3 show the distribution of genotypes of GSPT1-rs33635 and GSPT2-rs974285 in all groups, we found no statistical association between the genotypes and the presence of HBV infection, HBV NC, LC development from CHB, HCC development from CHB and LC in three models. This evidence concerns the gene GSPT2 and laryngotracheoesophageal cleft.