MAPT and Alzheimer disease: Of note, we excluded eight patients with CBS who fulfilled criteria for a CSF profile that was indicative of underlying AD pathology—defined as a CSF tau:Aβ1–42>1.15 In addition, all PSP cases from cohort 1 fulfilled probable RS criteria while the breakdown of cohort 2 PSP cases fulfilling probable criteria were as follows: 15 RS; 4 PSP-P; 2 PAGF.