Correlation of TMB and tumor PD-1+ 4-1BB+ CD8 T cells at baseline (A) in all patients, (B) in MM patients, (C) in all patients except MM; PD-L1 MPS and tumor PD-1+ 4-1BB+ CD8 T cells at baseline (D) in all patients, (E) in MM patients, (F) in all patients except MM; TMB and PD-L1 MPS at baseline (G) in all patients, (H) in MM patients, (I) in all patients except MM; and tumor PD-1+ 4-1BB+ CD8 T cells at baseline with fold-expansion of (J) tumor CD8 T cells and (K) tumor CD4 T cells. Here, CD8A is linked to neoplasm.