(Fig. 5a–e, no. of migration GBM cells, SBE4-TRAIL vs. control: 49.8 vs. 151.2, p < 0.001; migration distance of GBM cells, SBE4-TRAIL vs. control: 1.35 mm vs 3.40 mm, p < 0.001; maximum of tumor size, SBE4-TRAIL vs. control: 1.05 mm2 vs. 2.76 mm2, p < 0.01). Here, TNFSF10 is linked to glioblastoma.