Our previous study reported the reduced expression of myelin basic protein (Mbp), proteolipid protein (Plp) and myelin-oligodendrocyte glycoprotein (Mog), and downregulation of Olig1 and Olig2 in the corpus callosum, suggesting a hypomyelination in NPC mice [10]. The gene discussed is OLIG2; the disease is nasopharyngeal carcinoma.