SERPING1 and acquired angioedema: AAE-C1-INH patients have (1) a higher number of facial swellings (29.6% versus 1.6%), (2) a lower number of extremity swellings (25.7% versus 45.1%), and (3) a higher number of tongue swellings (1.8% versus 0.3%) than the HAE-C1-INH patients.