The result revealed that 5% (24/478) of cases of GC exhibited OLFML2B alteration, including missense mutation (14/478), amplification (9/478), mRNA upregulation (1/478) and deep deletion (1/478) (Fig. 6a), in addition, a number of neighboring genes in stomach neoplasms that were associated with OLFML2B were invested from Coexpedia to understand the molecular mechanism of GC (Fig. 6b). Here, OLFML2B is linked to gastric neoplasm.