Sites cg01268824 (ZNF154), cg22674699 (HOXD9), cg18081940 (TDRD10), and cg04475027 (TMEM132C) localized to gene promoter regions, were hypermethylated, and were negatively correlated with expression in breast tumor tissue, suggesting that DNA methylation at these sites may silence gene transcription (Table 1). This evidence concerns the gene ZNF154 and breast neoplasm.