In accordance with these observations, a large-scale genomic analysis of METABRIC and TCGA databases allowed us to assess not only that FGFR1 represents the most amplified receptor of the FGFRs family members but also that FGFR1 amplification occurs in nearly 14% of breast cancer patients (Figure 4a,b) [38,39]. This evidence concerns the gene FGFR1 and breast carcinoma.