This approach identified seven candidate PCa-specific hypermethylation markers (cg12799885, C2orf43, C2orf88, FBXO30-cg23095615, FBXO30-cg09094393, MOB3B and TPM4), all of which were suitable for the qMSP assay design and were selected for further validation (see Section 2.2 below). This evidence concerns the gene MOB3B and posterior cortical atrophy.