DOCK2 and posterior cortical atrophy: For six of the candidates (cg12799885, DOCK2, GRASP, HIF3A, PFKP and TPM4), there was a significant correlation between high methylation levels and a high CAPRA-S score (p < 0.05, Wilcoxon Mann–Whitney test; Figure 5), suggesting that higher methylation levels are linked with more aggressive PCa.