Substantial evidence has documented a positive proinflammatory profile in patients with idiopathic major depression including increases in circulating proinflammatory cytokines, interleukin (IL)-1, IL-6, tumor necrosis factor (TNF)-alpha, and C-reactive protein (CRP) [15], which correlates with depression severity [15,16]. The gene discussed is IL6; the disease is depressive symptom measurement.