MAPK3 and neuroblastoma: In SH-SY5Y cells, DUSP5 mRNA upregulation correlated with ERK1/2 activation conditions, illustrating that upregulation of ERK1/2-specific MKPs in NB cells is concomitant to the activation of ERK1/2 pathway, and DUSP5 siRNA knock-down resulted in increased cell proliferation.