We have previously shown that the expression of activity-dependent neuroprotective protein (ADNP), a protein vital for brain formation [11, 12], is correlated with Tau3R expression [13] and Adnp+/- mice exhibit tauopathy features—significant increase in phosphorylated Tau, prevented by treatment of ADNP-derived peptide NAP (NAPVSIPQ) [14] as well as tangle-like structures. This evidence concerns the gene MAPT and tauopathy.