Hafner et al demonstrated that 26 of 72 cases of epidermal nevus had HRAS mutations, the major ones of which result in p.G13R, not p.G12S substitution.6HRAS mutations were also observed in 62 of 65 and in 30 of 36 sebaceous nevus cases.7, 8 Almost all mutations result in p.G13R, not p.G12S substitutions.7 A heterozygous HRAS p.G12S mutation was demonstrated in the epidermal nevi of our case. Here, HRAS is linked to nevus, epidermal.