Immunofluorescence and live‐cell studies with MA‐10 mouse tumor Leydig cells revealed that treatment with di‐butyryl‐cAMP induced peroxisomes to approach mitochondria.135 It is suggested that the acyl‐CoA‐binding protein ACBD2/ECI2 inserts head to tail into peroxisomes and mitochondria. Here, ECI2 is linked to neoplasm.