TGFB1 and renal cell carcinoma: Since no remarkable changes of EMT marker patterns were detected with increasing amounts of TGF-β1 (10–100 ng/mL, Supplementary Figure 2A), the RCC cell lines were investigated whether they partially or irreversibly transit to the mesenchymal cell type with 10 ng/mL TGF-β1 within a time span of 96 h (a longer time did not considerably increase the response to the TGF-β1 stimulus, see Supplementary Figure 2B).