Antibodies against ENO1 have been described in Hashimoto's encephalopathy, Behçet's disease, Crohn's disease, rheumatoid arthritis (61–65) Recently, antibodies against citrullinated ENO1 (Anti-CEP-1) peptides have also been observed in pSS (66) and this raises the question if such autoantibodies associate with fatigue. Here, ENO1 is linked to rheumatoid arthritis.