Moreover, when analyzing tumors 10 days post vaccination, we observed that the frequency of OVA-specific CTLs infiltrating the tumors of Xcl1-(OVA SLP)-Fc- and Xcl1-Fc + OVA SLP-immunized mice was only 2–3 fold lower in the absence of OT-1 cell transfer (Figure 5B), which confirmed their efficient homing to the tumor, as compared to mice vaccinated with free OVA SLP + free Xcl1. Here, XCL1 is linked to neoplasm.