In male schizophrenia, SNCA was a strong predictor for state (AUC 100%, p = 0.014), in male depression STX11 was a strong predictor for trait first-year hospitalizations (AUC 100%, p = 0.00047), and in male depression ANK2 was a strong predictor for trait all future hospitalizations (OR 76.81, p = 0.0081). The gene discussed is ANK2; the disease is schizophrenia.