TF and infection: We crossed C57BL/6 MIP-TF mice with C57BL/6 Avy mice to determine whether MHV68-EGFP infection of the resulting obese MIP-TF Avy mice, as compared to their nonobese MIP-TF littermates, would lead to intra-insulitis and spreading of T cell autoreactivity from EGFP to other ß-cell antigens.