MIP and infection: Specifically, we were initially interested whether infection with a recombinant adenovirus, lymphocytic choriomeningitis virus (LCMV) or murine gammaherpesvirus-68 virus (MHV68) that directed the expression of EGFP could break self-tolerance to GFP in “MIP-GFP” mice that express GFP in their ß-cells23, and if so, would this neo-autoreactivity spread to other ß-cell antigens, promoting insulitis and T1D?