Two sub-units of NMDARS, NR2A and NR2B (also known as Grin2A and Grin2B) as well as several AMPARs including the metabotropic glutamate receptors 1 and 2 (mGlu-R1 and mGlu-R2), Gria3, Grm2, Grm4, Grik3 and Grik5 were up-regulated in the pup brain on P7 in response to maternal nematode infection. The gene discussed is GRIA3; the disease is Nematoda infectious disease.