IL1B and systemic lupus erythematosus: Expression of the pro-inflammatory cytokine gene, IL-1β, was down-regulated, the cytokine-cytokine receptor interaction pathway was down-regulated (Supplementary Dataset 6), and several autoimmune disease pathways associated with Th1 immune activation were down-regulated (autoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, asthma) (Supplementary Dataset 6).