The specific relationships between VEGF members and VEGFR isoforms in CRC were supported by our findings of positive correlations of VEGFR-1 with VEGF-A, -B, and PlGF; VEGFR-2 with VEGF-A, -C, and –D; and VEGFR-3 with VEGF-C and -D. This evidence concerns the gene FLT1 and colorectal carcinoma.