Splenic CD4+ T cells of Stim1/2Foxp3 mice also showed higher Ki-67 expression compared to WT control mice (Fig. 2c) suggesting that enhanced T cell proliferation contributes to the splenomegaly and lymphadenopathy of Stim1/2Foxp3 mice (Fig. 2a, Supplementary Figure 1c, d). Here, CD4 is linked to Lymphadenopathy.