“Classic” HGPS is caused by a point mutation in the LMNA gene (c.1824C>T;p.G608G), which activates a cryptic splice site in exon 11, leading to deletion of 150 nucleotides in the mRNA (De Sandre‐Giovannoli et al, 2003; Eriksson et al, 2003). The gene discussed is LMNA; the disease is Hutchinson-Gilford progeria syndrome.