HUVEC cells transduced with a lentivirus system encoding mTagRFP-mWasabi-LC3, which allows differentiation of autophagosomes (Wasabi+/RFP+ puncta) from autolysososmes (RFP+ puncta), demonstrated an increase in the autophagic flux from 18 to 24 hpi following infection with ZIKV strain GZ01 [139]. The gene discussed is MAP1LC3A; the disease is infection.