On the contrary, another study showed a significant enhancement in progeny virus particle production at 24 and 48 hpi but not at 72 hpi following infection with WNV-NY99 at MOI 0.01 in Atg5−/− MEFs when compared to Atg5+/+ MEFs or Atg5−/− cells back-transfected with Atg5 [133]. This evidence concerns the gene ATG5 and infection.