In the tertiary analysis the G-allele of rs10421768 in HAMP had an OR of 0.81 (95% CI 0.69–0.95, p = 0.0090) for development of stage 2 or 3 AKI; however, none of the variants had a statistically significant association in this adjusted model with CKD patients included (Table S1, ESM). This evidence concerns the gene HAMP and chronic kidney disease.