Up-regulation of AP001056.1 and down-regulation of ICOSLG was seen in tumors compared to tumor-free samples (p = 0.002, Figure 3a,b), and a significantly positive correlation between these two RNAs was seen in the tumors (Spearman’s rank correlation coefficient r = 0.867, p < 0.001) but not in the tumor-free controls (Figure 3c). The gene discussed is ICOSLG; the disease is neoplasm.