Castren et al., [73] reported that differentiation of neurospheres derived from post mortem human FXS brain and control fetal brain showed differences in neurite length, number, morphology, and altered Tuj1 to GFAP ratio while Bhattacharyya et al. [74] found no significant difference in neurons differentiated from FXS and healthy samples. This evidence concerns the gene GFAP and fragile X syndrome.