Relative to the mice with induced tongue cancer in the control group, the LF-CQPC08-H treatment greatly upregulated the mRNA expression of Nrf2, HO-1, and GST-π in the mouse town tissues, reaching nearly the levels of Nrf2, HO-1, and GST-π mRNA expression in the mouse tongue tissues of the normal group. The gene discussed is NFE2L2; the disease is tongue cancer.