Circulating galectin‐9 and CXCL10 levels could therefore be a direct reflection of active, interferon‐driven inflammation, which is supported by a recent study in which galectin‐9 was demonstrated to be a marker for the interferon signature in SLE and antiphospholipid syndrome 57. This evidence concerns the gene CXCL10 and systemic lupus erythematosus.