As displayed in Figure 5, the activities of SOD, GSH-Px, and CAT were obviously decreased in heart tissues of CHF group compared with the control group (34.97%, 32.16% and 61.61%, respectively; p < 0.05), and the content of MDA was obviously increased in CHF group compared with the control group (141.09%, p < 0.05). This evidence concerns the gene SOD1 and congestive heart failure.