However, IL-1β expression in hyperammonemic rats is increased in neurons of the CA1 region, not in astrocytes, in agreement with previous reports in rats with hyperammonemia and hepatic encephalopathy (Hernandez-Rabaza et al., 2015; Dadsetan et al., 2016b; Balzano et al., 2019). This evidence concerns the gene IL1B and Hyperammonemia.