In paired primary tumours and ovarian metastases samples, 5 out of 20 cases were HER2 positive in both primary tumours and ovarian metastases, 4 cases were HER2 positive in only primary tumours, and 5 cases were only positive in ovarian metastases, 9 cases were EGFR positive in both primary tumours and ovarian metastases, 5 cases were EGFR positive in only primary tumours, and 3 cases were only positive in ovarian metastases. This evidence concerns the gene EGFR and neoplasm.