TNF and hypertensive disorder: Here we present an alternative possibility of producing preeclamptic findings – high blood pressure, proteinuria, increased TNF-α and reduced PLGF levels in the serum, reduced weight of offspring at birth, and increased seizure susceptibility in vivo and in vitro – achieved through the effects of reduced blood supply to the left (for convenience) kidney by means of the clipping of the left renal artery of female Wistar rats.