Interestingly, however, while most literature consider MIM as a metastasis or tumour suppressor, at the same time, upregulation of MIM in hepatocellular and head and neck squamous cell carcinomas, as well as correlation of overexpression of MIM and poor prognosis in colorectal cancer has been reported23–25. Here, MTSS1 is linked to head and neck squamous cell carcinoma.