Using the dataset of 17 CLL patients, selected based on clinical (RAI, Binet staging and prognosis) and biological parameters (IgHV mutational status, CD38 and ZAP70 expression), we went on to measure the levels of MTSS1 transcript by real-time PCR in these patient samples. The gene discussed is MTSS1; the disease is B-cell chronic lymphocytic leukemia.