In order to stimulate the gland stem/progenitor cell proliferation, several cell growth factors were added including epidermal growth factor (EGF)33,34, basic fibroblast growth factor (bFGF)35, and anhidrotic ectodermal dysplasias (EDAs)36,37, which were found previously to be involved in the development of skin. This evidence concerns the gene EGF and Anhidrotic ectodermal dysplasia.