Analogously, top predicted DU (DD) rescuers of anti‐CTLA4 therapy were upregulated (downregulated) in post‐treatment tumor biopsies derived from patients treated with anti‐CTLA4 therapy (paired Wilcoxon P < 5E‐11, Fig 6C; see Dataset Table EV29 for pathways enrichment). Here, CTLA4 is linked to neoplasm.