Interestingly, the combination of DNT cell injection with anti-PD-1 resulted in an additional 43.1 ± 29.4% reduction of tumor volume (from 546.5 ± 125.7 mm3 in the DNT cell alone treated group to 310.7 ± 160.9 mm3 in the combination group) by day 20 (Fig. 4b). The gene discussed is PDCD1; the disease is neoplasm.