In univariate logistic regression analyses, baseline values such as younger age, male sex, lower body weight, shorter duration of diabetes, higher diastolic BP, higher TG level, higher eGFR, lower C-peptide level, no micro/macroalbuminuria, smaller mean CIMT, no use of statins, no use of CCBs or ACE inhibitors/ARBs, and no use of an anti-platelets/anti-coagulants were significantly associated with composite events of CAN recovery. Here, ACE is linked to Crouzon syndrome-acanthosis nigricans syndrome.