Mouse embryonic fibroblasts (MEFs) with genetic susceptibility can transform after WT Salmonella infection because effectors of the T3SS increase AKT and MAP kinase activities, whereas mutant Salmonella lacking effectors SopB, SopE, SopE2, and SptP cannot activate the AKT and MAP kinase [119]. Here, AKT1 is linked to Salmonella Infections.