Although the T cell responses we measured were limited to two immunodominant HCMV proteins, we did observe a significantly greater median HCMV-specific T cell response in the NKG2Cnull group, which is consistent with the idea of HCMV infection placing greater demand on adaptive immunity to control HCMV in the setting of NKG2C deficiency. The gene discussed is KLRC2; the disease is cytomegalovirus infection.