INS and prediabetes syndrome: Elevations in postprandial insulin correlated with larger increases in AV− CD31+ EVs following a 75-g OGTT in obese adults with and without prediabetes, see Figure 3A. Although not statistically significant, we report trends for increased circulating insulin at 120 min correlating with elevated post-prandial AV+ CD105 (r = 0.45, P = 0.06) and AV− CD45+ (r = 0.48, P = 0.04).