Interestingly, however, the genes coding for ubiquitin D, cathelicidin antimicrobial peptide (CAMP), neutrophil granule protein (NGP), lymphocyte antigen 6 complex, locus A (Ly6a), calcium binding protein (S100A8), calcium and zinc binding protein (S100A9), guanylate binding proteins, and indoleamine 2,3-dioxygenase were highly up-regulated in response to infection. The gene discussed is S100A9; the disease is infection.