The current study has elucidated the role of NF-κB in inflammatory eye diseases and the activation of NF-κB by F. It is important to note that in addition to inflammatory eye diseases, other inflammatory health diseases associated with NF-κB activation include asthma, COPD, atherosclerosis, rheumatoid arthritis, inflammatory bowel disease, diabetes, osteoporosis and cancer [143,149,290,291,292,293,294]. Here, NFKB1 is linked to rheumatoid arthritis.