Olaparib, Niraparib, Veliparib, and Rucaparib that are in different phases of research and clinical trials for cancers including HGSC may be evaluated in the CCM-Class for PARP1 as a potential therapeutic target [45,46] (ClinicalTrials.gov Identifier: NCT00535119, NCT00664781, and NCT00516373). The gene discussed is PARP1; the disease is cancer.